Sequence capture


Sequence capturesearch for term

Technology that enables one to retrieve target sequences specifically by hybridizing target DNA onto bait sequences on a solid support (slide or bead). (Langridge 2010). This uses oligonucleotide microarrays or oligonucleotide coupled beads to select for regions of the genome, such as all exons (exome sequencing) for targeted sequencing. (Hawkins 2010)