Balanced gene drive model
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This model derives from the gene balance hypothesis. Duplicates are retained only because were they fractionated back to one copy, the gene dosage change would confer a loss of fitness (haploinsufficiency). Retention is instantaneous, a neutral by-product or spandrel of ever-present purifying selection. This model is unique in predicting the reciprocal relationship between frequencies of retained genes posttandem duplication versus postwhole-genome duplication. (Freeling 2009)
